Article
Roles of cytoplasmic arginine and threonine in chloride transport by the bacteriorhodopsin mutant D85T.
Biophysical journal - 1 May 2001
Paula S, Tittor J, Oesterhelt D
Abstract excerpt
In the light-driven anion pump halorhodopsin (HR), the residues arginine 200 and threonine 203 are involved in anion release at the cytoplasmic side of the membrane. Because of large sequence homology and great structural similarities between HR and bacteriorhodopsin (BR), it has been suggested that anion translocation by HR and by the chloride-pumping BR mutant BR-D85T occurs by the same mechanism. Consequently,...
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