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Article

Crystal structure of the bromide-bound D85S mutant of bacteriorhodopsin: principles of ion pumping.

Biophysical journal - 1 Jul 2003

Facciotti Marc T, Cheung Vincent S, Nguyen Doris, Rouhani Shahab, Glaeser Robert M

Abstract excerpt

We report the crystal structure of a bromide-bound form of the D85S mutant of bacteriorhodopsin, bR(D85S), a protein that uses light energy rather than ATP to pump halide ions across the cell membrane. Comparison of the structure of the halide-bound and halide-free states reveals that both displacements of individual side-chain positions and concerted helical movements occur on the extracellular side of the...

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Identifiers

PMID: 12829500
DOI: 10.1016/S0006-3495(03)74490-7
PMCID: PMC1303101

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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