Article
Conversion of bacteriorhodopsin into a chloride ion pump.
Science (New York, N.Y.) - 7 Jul 1995
Sasaki J, Brown L S, Chon Y S, Kandori H, Maeda A, Needleman R, Lanyi J K
Abstract excerpt
In the light-driven proton pump bacteriorhodopsin, proton transfer from the retinal Schiff base to aspartate-85 is the crucial reaction of the transport cycle. In halorhodopsin, a light-driven chloride ion pump, the equivalent of residue 85 is threonine. When aspartate-85 was replaced with threon...
Topics
- Aspartic Acid
- Bacteriorhodopsins
- Biological Transport
- Chlorides
- Halorhodopsins
- Hot Temperature
- Hydrogen Bonding
- Hydrogen-Ion Concentration
- Ion Pumps
- Light
- Mutation
- Proton Pumps
- Schiff Bases