Article
Role of Arg123 in light-driven anion pump mechanisms of pharaonis halorhodopsin.
Photochemistry and photobiology - 1 Jan 2000
Kubo Megumi, Kikukawa Takashi, Miyauchi Seiji, Seki Akiteru, Kamiya Masakatsu, Aizawa Tomoyasu, Kawano Keiichi, Kamo Naoki, Demura Makoto
Abstract excerpt
Halorhodopsin (HR) acts as a light-driven chloride pump which transports a chloride ion from the extracellular (EC) to the cytoplasmic space during a photocycle reaction that includes some photointermediates initiated by illumination. To understand the chloride uptake mechanisms, we focused on a basic residue Arg123 of HR from Natronomonas pharaonis (NpHR), which is the only basic residue located in the EC half...
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