Article
Mutations conferring SO42- pumping ability on the cyanobacterial anion pump rhodopsin and the resultant unique features of the mutant.
Scientific reports - 30 Sept 2022
Doi Yuhei, Watanabe Jo, Nii Ryota, Tsukamoto Takashi, Demura Makoto, Sudo Yuki, Kikukawa Takashi
Abstract excerpt
Membrane transport proteins can be divided into two types: those that bind substrates in a resting state and those that do not. In this study, we demonstrate that these types can be converted by mutations through a study of two cyanobacterial anion-pumping rhodopsins, Mastigocladopsis repens halorhodopsin (MrHR) and Synechocystis halorhodopsin (SyHR). Anion pump rhodopsins, including MrHR and SyHR, initially bind...
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