Article
A helical lid converts a sulfotransferase to a dehydratase.
Nature structural biology - 1 May 2001
Pakhomova S, Kobayashi M, Buck J, Newcomer M E
Abstract excerpt
We report here the crystal structure of retinol dehydratase, an enzyme that catalyzes the synthesis of anhydroretinol. The enzyme is a member of the sulfotransferase superfamily and its crystal structure reveals the insertion of a helical lid into a canonical sulfotransferase fold. Site-directed...
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