Article
Expression of the orpk disease gene during kidney development and maturation.
Pediatric nephrology (Berlin, Germany) - 1 Mar 2001
Nakanishi K, Sweeney W E, Avner E D, Murcia N S
Abstract excerpt
Further analysis of the orpk mouse model of human autosomal recessive polycystic kidney disease is providing more insight into the function of the Tg737 gene and the pathobiology of renal cystic disease. Here we have determined the temporal-spatial profile of Tg737 expression and ascertained the profile of disease pathology utilizing Tg737delta2-3betaGal/+ and Tg737delta2-3betaGal/ Tg737orpk compound...
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