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Transgenic Xenopus laevis Line for In Vivo Labeling of Nephrons within the Kidney

6 Apr 2018

Abstract excerpt

Xenopus laevis embryos are an established model for studying kidney development. The nephron structure and genetic pathways that regulate nephrogenesis are conserved between Xenopus and humans, allowing for the study of human disease-causing genes. Xenopus embryos are also amenable to large-scale screening, but studies of kidney disease-related genes have been impeded because assessment of kidney development has...

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PMID: 29642376
DOI: 10.3390/genes9040197

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