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Article

Delayed cystogenesis and increased ciliogenesis associated with the re-expression of polaris in Tg737 mutant mice.

Kidney international - 1 Apr 2003

Brown Nicole E, Murcia Noel S

Abstract excerpt

BACKGROUND: Renal cysts and shortened cilia on renal tubular epithelia have been observed in Tg737orpk (orpk) mutant mice, suggesting a potential connection between cystogenesis and ciliogenesis. To further test this hypothesis we have characterized the progression of cystic disease and cilia expression in orpk, orpk;Tg737Rsq (orpk rescue), and Tg737 Delta 2-3 beta Gal;Tg737Rsq (KO rescue) mice. Methods. Orpk,...

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Identifiers

PMID: 12631338
DOI: 10.1046/j.1523-1755.2003.00863.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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