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Article

Implications of altered apoptosis in diabetes mellitus and autoimmune disease.

Apoptosis : an international journal on programmed cell death - 1 Jan 2000

Hayashi T, Faustman D L

Abstract excerpt

Lymphocyte development, selection and education represent tightly controlled immune processes that normally prevent autoimmunity. Lymphocyte development requires cellular selection through apoptosis to remove potentially autoreactive cells. Dysregulated apoptosis, both interrupted as well as accetuated apoptosis, are now demonstrated as central defects in diverse human and murine autoimmune disease. In murine...

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Identifiers

PMID: 11321039
DOI: 10.1023/a:1009667926296

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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