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Article

Host microarray analysis reveals a role for the Salmonella response regulator phoP in human macrophage cell death.

Proceedings of the National Academy of Sciences of the United States of America - 8 May 2001

Detweiler C S, Cunanan D B, Falkow S

Abstract excerpt

Bacterial pathogens manipulate host cells to promote pathogen survival and dissemination. We used a 22,571 human cDNA microarray to identify host pathways that are affected by the Salmonella enterica subspecies typhimurium phoP gene, a transcription factor required for virulence, by comparing the expression profiles of human monocytic tissue culture cells infected with either the wild-type bacteria or a phoPTn10...

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Identifiers

PMID: 11320214
DOI: 10.1073/pnas.091110098
PMCID: PMC33302

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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