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Article

Flagellin is the major proinflammatory determinant of enteropathogenic Salmonella.

Journal of immunology (Baltimore, Md. : 1950) - 1 Oct 2003

Zeng Hui, Carlson Adam Q, Guo Yanwen, Yu Yimin, Collier-Hyams Lauren S, Madara James L, Gewirtz Andrew T, Neish Andrew S

Abstract excerpt

The gastroenteritis-causing pathogen Salmonella typhimurium induces profound transcriptional changes in intestinal epithelia resulting in the recruitment of neutrophils whose presence is the histopathologic hallmark of salmonellosis. Here we used cDNA microarray expression profiling to define the molecular determinants that mediate such changes in model intestinal epithelia. Enteropathogenic Salmonella induced a...

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Source

Identifiers

PMID: 14500664
DOI: 10.4049/jimmunol.171.7.3668

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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