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Differential Immune Phenotypes in Human Monocytes Induced by Non-Host-Adapted Salmonella enterica Serovar Choleraesuis and Host-Adapted S. Typhimurium.

Infection and immunity - 1 Oct 2018

Ibrahim Hiba, Askar Basim, Hulme Scott, Neilson Peter, Barrow Paul, Foster Neil

Abstract excerpt

We studied the effects of two Salmonella enterica serovar Typhimurium (host-adapted) strains (14028 and 4/74) and three S Choleraesuis (non-host-adapted) strains (A50, A45, and B195) in human monocytes between 2 and 24 h postinfection (p.i.) to investigate whether differences in immune response may explain the much higher prevalence of sepsis in individuals infected with S Choleraesuis. Both serovars...

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PMID: 30037797
DOI: 10.1128/IAI.00509-18
PMCID: PMC6204746

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TNF

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