Article
Sequence variations of hepatitis B virus promoter regions in persistently infected patients.
Archives of virology - 1 Jan 2001
Ha-Lee Y M, Lee J, Pyun H, Kim Y, Sohn J, Cho Y J, Kim Y
Abstract excerpt
The HBV in the sera of two chronic active hepatitis patients were analyzed for the promoter sequence heterogeneity. In most cases, the proportion of any particular clone in the total viral populations was less than 50%, showing high mutation rates. In contrast, promoter sequences of HBV from asymptomatic carriers revealed only a few point mutations with no deletions. HBV in chronic patient harbored variants with...
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