Article
A new core promoter mutation and premature stop codon in the S gene in HBV strains from Iranian patients with cirrhosis.
Journal of viral hepatitis - 1 Apr 2009
Veazjalali M, Norder H, Magnius L, Jazayeri S M, Alavian S M, Mokhtari-Azad T
Abstract excerpt
In order to define hepatitis B virus (HBV) mutational patterns in Iran, nucleotide sequences obtained from 91 patients and encompassing the precore, basal core promoter (BCP) and surface (S) regions, were compared. The patients were grouped as asymptomatic carriers, chronic active hepatitis or cirrhotic patients. Genotypes and mutations were determined by sequencing and phylogenetic analysis. All strains belonged...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
