Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A simple polymerase chain reaction assay for genotyping the retinal degeneration mutation (Pdeb(rd1)) in FVB/N-derived transgenic mice.

Laboratory animals - 1 Apr 2001

Giménez E, Montoliu L

Abstract excerpt

FVB/N mice are one of the most common inbred strains for the generation of transgenic animals. This mouse strain is preferred for transgenesis because of its fertilized oocytes, which have unique pronuclei for microinjection, and its vigorous reproductive performance along with consistently large litter sizes. However, these inbred mice carry a retinal degeneration mutation caused by a proviral insertion into the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3',5'-Cyclic-GMP Phosphodiesterases
Share to Crosses, Genetic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Inbred ICR

Share to Mice, Inbred Strains

Share to Mice, Transgenic

Share to Polymerase Chain Reaction

Share to Retinal Degeneration

Source

Identifiers

PMID: 11315164
DOI: 10.1258/0023677011911525

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A simple polymerase chain reaction assay for genotyping the retinal degeneration mutation (Pdeb(rd1)) in FVB/N-derived transgenic mice.PMID 11315164Read ↗

Review: the history and role of naturally occurring mouse models with Pde6b mutations.Semantic proximity Read ↗

Two mouse retinal degenerations caused by missense mutations in the beta-subunit of rod cGMP phosphodiesterase gene.Semantic proximity Read ↗

Functional rescue of degenerating photoreceptors in mice homozygous for a hypomorphic cGMP phosphodiesterase 6 b allele (Pde6bH620Q).Semantic proximity Read ↗

Genotype-phenotype correlation of mouse pde6b mutations.Semantic proximity Read ↗

A congenic C57BL/6J rd1 mouse model for retinal degeneration research.Semantic proximity Read ↗

Molecular biology tools for the study and therapy of PDE6β mutations.Semantic proximity Read ↗

AAV-mediated gene therapy for retinal degeneration in the rd10 mouse containing a recessive PDEbeta mutation.Semantic proximity Read ↗

Mutation spectrum of the gene encoding the beta subunit of rod phosphodiesterase among patients with autosomal recessive retinitis pigmentosa.Semantic proximity Read ↗

A Congenic C57BL/6 <i>rd1</i> Mouse Model for Retinal Degeneration ResearchSemantic proximity Read ↗

Gene therapy restores vision in rd1 mice after removal of a confounding mutation in Gpr179.Semantic proximity Read ↗

Irish setter dogs affected with rod/cone dysplasia contain a nonsense mutation in the rod cGMP phosphodiesterase beta-subunit gene.Semantic proximity Read ↗

AAV8-PDE6B with 3’UTR provides durable rescue of photoreceptor structure and function in rd10 mouse model of retinitis pigmentosaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.