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Article

Molecular biology tools for the study and therapy of PDE6β mutations.

Journal of biotechnology - 20 Oct 2018

Bitoque Diogo B, Silva Gabriela A

Abstract excerpt

Gene therapy has the potential for treating retinal diseases, and we have been developing delivery vehicles and expression vectors for this purpose. In this short communication, we describe the generation of tools for both in vitro studies of the disease mechanism and for in vivo testing of therapeutic approaches. We have cloned the PDE6β gene and also recreated the same mutation present in the rd10 mouse using...

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Share to Cyclic Nucleotide Phosphodiesterases, Type 6
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 30053498
DOI: 10.1016/j.jbiotec.2018.07.030

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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