Article
Therapeutic efficacy of G207 in a novel peripheral nerve sheath tumor model.
Experimental neurology - 1 May 2001
Mashour G A, Moulding H D, Chahlavi A, Khan G A, Rabkin S D, Martuza R L, Driever P H, Kurtz A, Chalavi A
Abstract excerpt
Nerve involvement poses a significant obstacle for the management of peripheral nervous system tumors, and nerve injury provides a frequent source of postoperative morbidity. The lack of suitable animal models for peripheral nerve tumors has impeded the development of alternative nerve-sparing therapies. To evaluate the effect of a multimutated replication-competent herpes simplex virus (G207) on the growth of...
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