Article
Attenuated multimutated herpes simplex virus-1 effectively treats prostate carcinomas with neural invasion while preserving nerve function.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jun 2008
Kelly Kaitlyn, Brader Peter, Rein Avigail, Shah Jatin P, Wong Richard J, Fong Yuman, Gil Ziv
Abstract excerpt
Many cancers can cause disability and pain by invading nerves. In particular, prostate carcinoma has a high propensity for neural invasion (NI) at an early stage. Attempted surgical treatment of tumors with NI often leads to erectile dysfunction and deteriorated quality of life. Therefore, there is a need for novel modalities that will selectively target cancer cells while preserving neural function. Herpes...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.