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Article

Immuno-viral therapy as a new approach for the treatment of brain tumors.

Drug news & perspectives - 1 May 2003

Toda Masahiro

Abstract excerpt

The central nervous system (CNS) has been considered an immunologically privileged site; however, recent evidence suggests that activated T cells cross the intact blood-brain barrier and that a series of immunological events is initiated when T cells recognize CNS antigens. Therefore, brain tumors might be selectively eliminated by T cells activated with antigens specific for the tumors. Using a conditionally...

Topics

Brain Neoplasms
Cancer Vaccines
Cytotoxicity, Immunologic
Herpesvirus 1, Human
Humans
Immunotherapy
Lymphocyte Activation
Mutation
Neoplasm Metastasis
T-Lymphocytes
Virus Replication

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12942152
DOI: 10.1358/dnp.2003.16.4.829334

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