Article
Peripheral nerve injury mediated by JEV strain NX1889 infection and impairment of Schwann cells.
PLoS neglected tropical diseases - 1 Aug 2025
Yang Liping, Yuan Yanping, Yin Qikai, Li Xiaocong, Kang Xue, Cui Qianqian, Wang Guowei, Yang Huan, Wang Ruichen, Yang Tingting, Li Fan, Fu Shihong, Wang Huanyu, Wang Zhenhai
Abstract excerpt
Japanese encephalitis virus (JEV) is a mosquito-borne flavivirus primarily associated with central nervous system disorders. Recent studies have indicated that JEV infection can lead to Guillain-Barré syndrome (GBS), a peripheral nervous system (PNS) disorder; however, the underlying mechanisms remain unclear. In this study, we investigated the tropism of different genotypes of JEV strains for peripheral nerves...
Read the complete abstract on PubMedTopics
- Animals
- Schwann Cells
- Mice
- Encephalitis Virus, Japanese
- Peripheral Nerve Injuries
- Encephalitis, Japanese