Article
Association of 4F2hc with light chains LAT1, LAT2 or y+LAT2 requires different domains.
The Biochemical journal - 1 May 2001
Bröer A, Friedrich B, Wagner C A, Fillon S, Ganapathy V, Lang F, Bröer S
Abstract excerpt
Heterodimeric amino acid transporters are comprised of a type-II membrane protein named the heavy chain (4F2hc or rBAT) that may associate with a number of different polytopic membrane proteins, called light chains. It is thought that the heavy chain is mainly involved in the trafficking of the complex to the plasma membrane, whereas the transport process itself is catalysed by the light chain. The 4F2 heavy...
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