Article
Identification of a consensus motif for retention of transmembrane proteins in the endoplasmic reticulum.
The EMBO journal - 1 Oct 1990
Jackson M R, Nilsson T, Peterson P A
Abstract excerpt
Several families of transmembrane endoplasmic reticulum (ER) proteins contain retention motifs in their cytoplasmically exposed tails. Mutational analyses demonstrated that two lysines positioned three and four or five residues from the C-terminus represent the retention motif. The introduction of a lysine preceding the lysine that occurs three residues from the terminus of Lyt2 renders this cell surface protein...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.