Article
Identification and expression of cosmids with an allelic variant of class I alcohol dehydrogenase in transgenic mice.
Chemico-biological interactions - 30 Jan 2001
Szalai G, Ceci J, Dewey M, Felder M
Abstract excerpt
The mouse Adh1 gene exhibits tissue-specific regulation, is developmentally regulated, and is androgen regulated in kidney and adrenal tissue. To study this complex regulation phenotype a transgenic mouse approach has been used to investigate regulatory regions of the gene necessary for proper tissue expression and hormonal control. Transgenic mice have been produced with an Adh1 minigene as a reporter behind...
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