Human sex hormone-binding globulin gene expression in transgenic mice.

doi:10.1210/mend.12.1.0050

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Article

Human sex hormone-binding globulin gene expression in transgenic mice.

Molecular endocrinology (Baltimore, Md.) - 1 Jan 1998

Jänne M, Deol H K, Power S G, Yee S P, Hammond G L

Abstract excerpt

The sex hormone-binding globulin gene (shbg) is expressed in the liver and testis as well as in several other tissues that play important roles in reproduction. Expression of shbg in the human liver results in the production of plasma sex hormone-binding globulin (SHBG), which regulates the bioav...

Topics

Animals
Chromosome Mapping
Gene Expression Regulation
Humans
Male
Mice
Mice, Inbred C57BL
Mice, Inbred CBA
Mice, Transgenic
Organ Specificity
Phenotype
RNA, Messenger
Sex Hormone-Binding Globulin
Testosterone
Transcription, Genetic
Transgenes

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