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Article

SEPT12 phosphorylation results in loss of the septin ring/sperm annulus, defective sperm motility and poor male fertility.

PLoS genetics - 1 Mar 2017

Shen Yi-Ru, Wang Han-Yu, Kuo Yung-Che, Shih Shih-Chuan, Hsu Chun-Hua, Chen Yet-Ran, Wu Shang-Rung, Wang Chia-Yih, Kuo Pao-Lin

Abstract excerpt

Septins are critical for numerous cellular processes through the formation of heteromeric filaments and rings indicating the importance of structural regulators in septin assembly. Several posttranslational modifications (PTMs) mediate the dynamics of septin filaments in yeast. However, little is known about the role of PTMs in regulating mammalian septin assembly, and the in vivo significance of PTMs on...

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PMID: 28346465
DOI: 10.1371/journal.pgen.1006631
PMCID: PMC5386304

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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