Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Stathmin regulates centrosomal nucleation of microtubules and tubulin dimer/polymer partitioning.

Molecular biology of the cell - 1 Aug 2009

Ringhoff Danielle N, Cassimeris Lynne

Abstract excerpt

Stathmin is a microtubule-destabilizing protein ubiquitously expressed in vertebrates and highly expressed in many cancers. In several cell types, stathmin regulates the partitioning of tubulin between unassembled and polymer forms, but the mechanism responsible for partitioning has not been determined. We examined stathmin function in two cell systems: mouse embryonic fibroblasts (MEFs) isolated from embryos...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Centrosome
Share to Fluorescent Antibody Technique, Indirect
Share to Microtubule-Associated Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Microtubules

Share to Polymers

Share to Protein Multimerization

Share to Stathmin

Share to Tubulin

Source

Open in PubMed Open full text

Identifiers

PMID: 19515833
DOI: 10.1091/mbc.e09-02-0140
PMCID: PMC2719563

Genes

CFP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Stathmin regulates centrosomal nucleation of microtubules and tubulin dimer/polymer partitioning.PMID 19515833Read ↗

Stathmin: a protein with many tasks. New biomarker and potential target in cancerSemantic proximity Read ↗

Stathmin, a microtubule-destabilizing protein, is dysregulated in spinal muscular atrophy†Semantic proximity Read ↗

STNM1 in human cancers: role, function and potential therapy sensitizerSemantic proximity Read ↗

Differential effect of two stathmin/Op18 phosphorylation mutants on Xenopus embryo development.Semantic proximity Read ↗

Stathmin activity influences sarcoma cell shape, motility, and metastatic potential.Semantic proximity Read ↗

Microtubule-templated actin assembly by septin9 drives apical expansion of epithelial cellsSemantic proximity Read ↗

Stathmin-tubulin interaction gradients in motile and mitotic cells.Semantic proximity Read ↗

Stathmin is required for stability of the Drosophila neuromuscular junction.Semantic proximity Read ↗

Tubulin autoregulation factors SCAPER and TTC5 recruit γ-tubulin to non-centrosomal MTOCs for neuronal microtubule nucleation and axon regenerationSemantic proximity Read ↗

Ran-GTP is non-essential to activate NuMA for spindle pole focusing, but dynamically polarizes HURP to control mitotic spindle lengthSemantic proximity Read ↗

Effects of stathmin inhibition on the mitotic spindle.Semantic proximity Read ↗

The Microtubule Regulatory Protein Stathmin Is Required to Maintain the Integrity of Axonal Microtubules in Drosophila.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.