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Article

The beta-beta-alpha fold: explorations in sequence space.

Journal of molecular biology - 13 Apr 2001

Sarisky C A, Mayo S L

Abstract excerpt

The computational redesign of the second zinc finger of Zif268 to produce a 28 residue peptide (FSD-1) that assumes a betabetaalpha fold without metal binding was recently reported. In order to explore the tolerance of this metal-free fold towards sequence variability, six additional peptides resulting from the ORBIT computational protein design process were synthesized and characterized. The experimental...

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Identifiers

PMID: 11292351
DOI: 10.1006/jmbi.2000.4345

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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