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Article

Importance of alpha-helix N-capping motif in stabilization of betabetaalpha fold.

Protein science : a publication of the Protein Society - 1 Jun 2003

Koscielska-Kasprzak Katarzyna, Cierpicki Tomasz, Otlewski Jacek

Abstract excerpt

FSD-1 (full sequence design 1) is a protein folded in a betabetaalpha motif, designed on the basis of the second zinc finger domain of Zif268 by a substitution of its metal coordination site with a hydrophobic core. In this work, we analyzed the possibility of introducing the DNA recognition motif of the template zinc finger (S(13)RSDH(17)) into FSD-1 sequence in order to obtain a small DNA-binding module devoid...

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Identifiers

PMID: 12761399
DOI: 10.1110/ps.0301703
PMCID: PMC2323898

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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