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Article

The hidden thermodynamics of a zinc finger.

Journal of molecular biology - 1 Mar 2002

Lachenmann Marcel J, Ladbury John E, Phillips Nelson B, Narayana Narendra, Qian Xiuqi, Weiss Michael A

Abstract excerpt

The Zn finger provides a model for studies of protein structure and stability. Its core contains a conserved phenylalanine residue adjoining three architectural elements: a beta-hairpin, an alpha-helix and a tetrahedral Zn(2+)-binding site. Here, we demonstrate that the consensus Phe is not required for high-affinity Zn(2+) binding but contributes to the specification of a precise DNA-binding surface....

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Source

Identifiers

PMID: 11884136
DOI: 10.1006/jmbi.2001.5335

Genes

ZFY

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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