Article

Analysis of the HLA class I associated peptide repertoire in a hepatocellular carcinoma cell line reveals tumor-specific peptides as putative targets for immunotherapy.

2007-03-01

Abstract excerpt

HLA class I molecules present peptides on the cell surface to CD8+ T cells. The repertoire of peptides that associate to class I molecules represents the cellular proteome. Therefore, cells expressing different proteomes could generate different class I-associated peptide repertoires. A large number of peptides have been sequenced from HLA class I alleles, mostly from lymphoid cells. On the other hand, T cell immu...

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Identifiers and source

Literature Corpus work: a593ef88-bdc2-5870-adce-cfb73834da10
DOI: 10.1002/prca.200600388

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