Article
[Epitope of somatic mutations in the hepatocyte growth factor receptor naturally processed and presented by HLA-A2 on human hepatocellular carcinoma].
Zhonghua yi xue za zhi - 10 Jan 2001
Guo A, Sui Y, Ye J
Abstract excerpt
OBJECTIVE: To isolate and identify peptides bound to HLA I on human hepatocellular carcinoma. METHODS: MHC-associated peptides were extracted by mild acid wash of viable hepatocellular carcinomas cells, collected by gel filtration, and fractioned by reversed phase high pressured liquid chromatography (RP-HPLC). Peptides of individual fractions were reconstitution of T cell epitopes and were identified by...
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