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Article

The C677T methylenetetrahydrofolate reductase gene mutation in hemodialysis patients.

Journal of the American Society of Nephrology : JASN - 1 May 2000

Kimura Hideki, Gejyo Fumitake, Suzuki Satoru, Miyazaki Ryoichi

Abstract excerpt

Hyperhomocysteinemia, which results from renal impairment, may promote arteriosclerosis and glomerulosclerosis. The combined effect of renal failure and a common mutation (C677T) in the methylenetetrahydrofolate reductase gene that leads to serum homocysteine elevations in dialysis patients was investigated. Genotypes were determined at this locus in 545 dialysis patients and 676 healthy subjects, and serum...

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Share to Homocysteine
Share to Hyperhomocysteinemia
Share to Kidney Failure, Chronic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Linear Models

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Oxidoreductases Acting on CH-NH Group Donors

Share to Renal Dialysis

Share to Vascular Diseases

Source

Identifiers

PMID: 10770966
DOI: 10.1681/ASN.V115885

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The C677T methylenetetrahydrofolate reductase gene mutation in hemodialysis patients.PMID 10770966Read ↗

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