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Article

Role of nuclear factor κB in liver health and disease

30 Mar 2010

Abstract excerpt

NF-kappaB (nuclear factor kappaB) is a heterodimeric transcription factor that is constitutively expressed in all cell types and has a central role as a transcriptional regulator in response to cellular stress. In the present review, we discuss the role of NF-kappaB signalling in the maintenance of liver homoeostasis as well as in the pathogenesis of a wide variety of conditions affecting the liver, including...

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PMID: 20350292
DOI: 10.1042/cs20090549

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