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Article

Selecting SNPs in two-stage analysis of disease association data: a model-free approach.

Annals of human genetics - 1 Sept 2000

Hoh J, Wille A, Zee R, Cheng S, Reynolds R, Lindpaintner K, Ott J

Abstract excerpt

For large numbers of marker loci in a genomic scan for disease loci, we propose a novel 2-stage approach for linkage or association analysis. The two stages are (1) selection of a subset of markers that are 'important' for the trait studied, and (2) modelling interactions among markers and between markers and trait. Here we focus on stage 1 and develop a selection method based on a 2-level nested bootstrap...

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PMID: 11281279
DOI: 10.1046/j.1469-1809.2000.6450413.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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