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Article

The expression of vascular endothelial growth factor correlates with mutant p53 and poor prognosis in human breast cancer.

Cancer research - 1 Mar 2001

Linderholm B K, Lindahl T, Holmberg L, Klaar S, Lennerstrand J, Henriksson R, Bergh J

Abstract excerpt

Wild-type p53 protein has been shown to inhibit angiogenesis through thrombospondin in the preclinical setting. Here, we determined the associations between the expression of the angiogenic factor vascular endothelial growth factor (VEGF) and the p53 status, including different mutation sites and types, in primary breast cancer. Cytosols from 224 primary breast cancer patients were analyzed with an enzyme...

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PMID: 11280795

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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