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Article

MDA-MB-231 breast cancer cells overexpressing single VEGF isoforms display distinct colonisation characteristics

21 Jul 2015

Abstract excerpt

BACKGROUND: Vascular endothelial growth factor (VEGF) is a multifunctional cytokine that has important roles in angiogenesis. Our knowledge of the significance of VEGF isoforms in human cancer remains incomplete. METHODS: Bioluminescence imaging and transcriptomic analysis were used to study the colonisation capacity of the human breast cancer cells MDA-MB-231 controlling or overexpressing the VEGF165 or VEGF189...

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PMID: 26196186
DOI: 10.1038/bjc.2015.267

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