Article
Two active molecular phenotypes of the tachykinin NK1 receptor revealed by G-protein fusions and mutagenesis.
The Journal of biological chemistry - 8 Jun 2001
Holst B, Hastrup H, Raffetseder U, Martini L, Schwartz T W
Abstract excerpt
The NK1 neurokinin receptor presents two non-ideal binding phenomena, two-component binding curves for all agonists and significant differences between agonist affinity determined by homologous versus heterologous competition binding. Whole cell binding with fusion proteins constructed between ei...
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