Article
Split-receptors in the tachykinin neurokinin-1 system--mutational analysis of intracellular loop 3.
European journal of biochemistry - 15 Jan 1998
Nielsen S M, Elling C E, Schwartz T W
Abstract excerpt
Several membrane proteins have been functionally expressed from non-covalently coupled, contiguous segments especially with the split-site located between natural domains. Experiments using such 'split-proteins' were here performed in the tachykinin neurokinin-1 (NK1) receptor with co-expression...
Topics
- Amino Acid Sequence
- Animals
- Biphenyl Compounds
- COS Cells
- GTP-Binding Proteins
- Molecular Sequence Data
- Mutation
- Phosphatidylinositols
- Receptors, Neurokinin-1
- Recombinant Proteins
- Signal Transduction
- Substance P
