Article
Split-receptors in the tachykinin neurokinin-1 system--mutational analysis of intracellular loop 3.
European journal of biochemistry - 15 Jan 1998
Nielsen S M, Elling C E, Schwartz T W
Abstract excerpt
Several membrane proteins have been functionally expressed from non-covalently coupled, contiguous segments especially with the split-site located between natural domains. Experiments using such 'split-proteins' were here performed in the tachykinin neurokinin-1 (NK1) receptor with co-expression of contiguous segments with split-sites positioned in various intracellular and extracellular loops. The construct...
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