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Article

NK1 receptor fused to beta-arrestin displays a single-component, high-affinity molecular phenotype.

Molecular pharmacology - 1 Jul 2002

Martini Lene, Hastrup Hanne, Holst Birgitte, Fraile-Ramos Alberto, Marsh Mark, Schwartz Thue W

Abstract excerpt

Arrestins are cytosolic proteins that, upon stimulation of seven transmembrane (7TM) receptors, terminate signaling by binding to the receptor, displacing the G protein and targeting the receptor to clathrin-coated pits. Fusion of beta-arrestin1 to the C-terminal end of the neurokinin NK1 recepto...

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PMID: 12065752
DOI: 10.1124/mol.62.1.30

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12065752-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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