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Article

Involvement of domain 3 in oligomerization by the protective antigen moiety of anthrax toxin.

Journal of bacteriology - 1 Mar 2001

Mogridge J, Mourez M, Collier R J

Abstract excerpt

Protective antigen (PA), a component of anthrax toxin, binds receptors on mammalian cells and is activated by a cell surface protease. The resulting active fragment, PA(63), forms ring-shaped heptamers, binds the enzymic moieties of the toxin, and translocates them to the cytosol. Of the four crystallographic domains of PA, domain 1 has been implicated in binding the enzymic moieties; domain 2 is involved in...

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Identifiers

PMID: 11222612
DOI: 10.1128/JB.183.6.2111-2116.2001
PMCID: PMC95109

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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