Article
Polymorphisms in the promoter region and at codon 54 of the MBL2 gene are not associated with IgA nephropathy.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Apr 2001
Pirulli D, Boniotto M, Vatta L, Crovella S, Spano A, Morgutti M, Zezlina S, Bertola L, Roccatello D, Scolari F, Peruzzi L, Savoldi S, Amoroso A
Abstract excerpt
BACKGROUND: IgA nephropathy (IgAN) occurs sporadically in unrelated individuals. Several different polymorphic genes have been investigated in recent years in order to demonstrate their possible association with IgAN. Three recent, different studies with conflicting conclusions have discussed the role of the mannose binding lectin (MBL), a serum lectin involved in natural immunity, in the IgAN pathogenesis by...
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