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Article

Reduced oxidative-stress response in red blood cells from p45NFE2-deficient mice.

Blood - 1 Apr 2001

Chan J Y, Kwong M, Lo M, Emerson R, Kuypers F A

Abstract excerpt

p45NF-E2 is a member of the cap 'n' collar (CNC)-basic leucine zipper family of transcriptional activators that is expressed at high levels in various types of blood cells. Mice deficient in p45NF-E2 that were generated by gene targeting have high mortality from bleeding resulting from severe thrombocytopenia. Surviving p45nf-e2(-/-) adults have mild anemia characterized by hypochromic red blood cells (RBCs),...

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Identifiers

PMID: 11264184
DOI: 10.1182/blood.v97.7.2151

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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