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Article

Defective erythroid differentiation in miR-451 mutant mice mediated by 14-3-3zeta.

Genes & development - 1 Aug 2010

Patrick David M, Zhang Cheng C, Tao Ye, Yao Huiyu, Qi Xiaoxia, Schwartz Robert J, Jun-Shen Huang Lily, Olson Eric N

Abstract excerpt

Erythrocyte formation occurs throughout life in response to cytokine signaling. We show that microRNA-451 (miR-451) regulates erythropoiesis in vivo. Mice lacking miR-451 display a reduction in hematrocrit, an erythroid differentiation defect, and ineffective erythropoiesis in response to oxidati...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20679397
DOI: 10.1101/gad.1942810
PMCID: PMC2912559

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20679397-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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