Article
Inhibitory effect on natural killer activity of microphthalmia transcription factor encoded by the mutant mi allele of mice.
Blood - 1 Apr 2001
Ito A, Kataoka T R, Kim D K, Koma Y, Lee Y M, Kitamura Y
Abstract excerpt
The mouse mi locus encodes a basic-helix-loop-helix-leucine zipper-type transcription factor, microphthalmia transcription factor (MITF). Mice of mi/mi genotype express a mutant form of MITF (mi-MITF), whereas mice of tg/tg genotype have a transgene in the 5' flanking region of the mi gene and do...
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