Article
Inhibitory effect of the transcription factor encoded by the mi mutant allele in cultured mast cells of mice.
Blood - 15 Feb 1999
Ito A, Morii E, Kim D K, Kataoka T R, Jippo T, Maeyama K, Nojima H, Kitamura Y
Abstract excerpt
The mi locus of mice encodes a transcription factor of the basic-helix-loop-helix-leucine zipper protein family (MITF). The MITF encoded by the mutant mi allele (mi-MITF) deletes 1 of 4 consecutive arginines in the basic domain. The mice of mi/mi genotype express mi-MITF, whereas the mice of tg/t...
Topics
- Animals
- Cells, Cultured
- DNA-Binding Proteins
- Gene Expression Regulation
- Helix-Loop-Helix Motifs
- Leucine Zippers
- Mast Cells
- Mice
- Mice, Inbred C57BL
- Microphthalmia-Associated Transcription Factor
- Mutation
- Transcription Factors