Article
Deficient transcription of mouse mast cell protease 4 gene in mutant mice of mi/mi genotype.
Blood - 15 Mar 1999
Jippo T, Lee Y M, Katsu Y, Tsujino K, Morii E, Kim D K, Kim H M, Kitamura Y
Abstract excerpt
The mi locus encodes a member of the basic-helix-loop-helix-leucine zipper (bHLH-Zip) protein family of transcription factors (hereafter called MITF). We reported that expression of the mouse mast cell protease 5 (MMCP-5) and MMCP-6 genes were deficient in cultured mast cells (CMC) derived from mutant mice of mi/mi genotype. Despite the reduced expression of both MMCP-5 and MMCP-6, their regulation mechanisms...
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