Article
BRCA1 germline mutations in women with uterine serous papillary carcinoma.
Obstetrics and gynecology - 1 Jul 2000
Lavie O, Hornreich G, Ben Arie A, Renbaum P, Levy-Lahad E, Beller U
Abstract excerpt
OBJECTIVE: To determine the possible effects and incidence of BRCA1 and BRCA2 germline mutations in uterine serous papillary carcinoma. METHODS: We screened DNA from 12 women with uterine serous papillary carcinoma for BRCA1 and BRCA2 germline mutations common in the Jewish population (BRCA1-185delAG and 5382insC, BRCA2-6174delT). In women with germline mutations, tumor DNA was screened for loss of heterozygosity...
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