Article
The rate of the predominant Jewish mutations in the BRCA1, BRCA2, MSH2 and MSH6 genes in unselected Jewish endometrial cancer patients.
Gynecologic oncology - 1 Dec 2010
Barak Frida, Milgrom Roni, Laitman Yael, Gemer Ofer, Rabinovich Alex, Piura Benjamin, Anteby Eyal, Baruch Gilad Ben, Korach Jacob, Friedman Eitan
Abstract excerpt
OBJECTIVES: The genes associated with familial Endometrial Cancer (EC) are largely unknown. While EC is an integral part of Hereditary Non-Polyposis Colon Cancer, there is an ongoing debate if EC is indeed overrepresented in hereditary breast/ovarian cancer families. METHODS: Unselected Jewish women with EC who were diagnosed from January 1982 to January 2008 were genotyped for the predominant mutations in Jewish...
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