Article
Ovarian cancer risk in Ashkenazi Jewish carriers of BRCA1 and BRCA2 mutations.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Dec 2002
Satagopan Jaya M, Boyd Jeff, Kauff Noah D, Robson Mark, Scheuer Lauren, Narod Steven, Offit Kenneth
Abstract excerpt
PURPOSE: Several studies to date have reported ovarian cancer risk due to inherited BRCA1 and BRCA2 mutations using familial data or population-based series of probands. Familial aggregation associated with both of these methods may result in a substantial ascertainment bias. To address this, we have used a case-control design that does not involve familial aggregation to estimate the lifetime penetrance of...
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